Mec 1 p Regulate Chromosome Segregation and Chromosome Rearrangements in Saccharomyces cerevisiae by Jennifer
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چکیده
Tel1p and Mec1p Regulate Chromosome Segregation and Chromosome Rearrangements in Saccharomyces cerevisiae by Jennifer Lynn McCulley Department of Pharmacology and Cancer Biology Duke University Date:_______________________ Approved: ___________________________ Dr. Thomas D. Petes, Chair ___________________________ Dr. Sue Jinks-Robertson ___________________________ Dr. Daniel J. Lew ___________________________ Dr. Steven B. Haase ___________________________ Dr. Christopher M. Counter An abstract of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Pharmacology and Cancer Biology in the Graduate School of Duke University
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Initiation of Ageing Process by Meiotic and Mitotic Recombination within the Ribosomal DNA Genes in Saccharomyces cerevisiae
In the budding yeast of Saccharomyces cerevisiae the tandem repeated of rDNA genes are located onchromosome XII, which is in the nucleolus. There are different types of proteins in the nucleoluskeleton,silencing proteins have got important role in nucleolus.It is shown that meiotic recombination between nonsister chromatids in the rDNA genes are stronglysuppressed, and s...
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